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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T34862 | Thromboxane A2 | Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2 | |
Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction. | |||
T36548 | Carbocyclic Thromboxane A2 | ||
Carbocyclic Thromboxane A2 can be used in related research in the field of life sciences. Its product number is T36548 and CAS number is 74034-56-3. | |||
T36208 | 15(R)-Pinane Thromboxane A2 | 15(R)-Pinane Thromboxane A2 | |
15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 . 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM). It does not affect gastric tone in isolated rat gastric fun... | |||
T6236 | Ozagrel | OKY-046,Domenan | Thrombin , Prostaglandin Receptor |
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch... | |||
T6625 | Ozagrel hydrochloride | Ozagrel HCl,OKY-046 HCl | Thrombin , Prostaglandin Receptor |
Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. | |||
T12268 | NTP42 | Prostaglandin Receptor , PPAR | |
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM) | |||
T17039 | Terbogrel | BIBV 308SE | Prostaglandin Receptor |
Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a... | |||
T11339L | Furegrelate | PPAR | |
FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets. | |||
T31213 | Dazmegrel | UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485 | PPAR |
Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy. | |||
T12771 | RS-601 | Leukotriene Receptor , Thrombin | |
RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a guinea pig model of asthma. | |||
T27630 | Isbogrel | CV4151,CV-4151,CV 4151 | Prostaglandin Receptor |
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis. | |||
T11339 | Furegrelate sodium | U-63557A | PPAR |
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM. | |||
T68022L | Sulotroban potassium | BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base) | PPAR |
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis. | |||
T15049 | Daltroban | BM-13505,SKF 96148 | PPAR |
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells. | |||
T11825 | LCB-2853 | PPAR | |
LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects. | |||
T0212 | Seratrodast | AA 2414,ABT-001 | COX , Prostaglandin Receptor , PPAR |
Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained ma... | |||
T15577 | Indobufen | Ibustrin | COX |
Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue fac... | |||
TQ0145 | (R)-(+)-Bay-K-8644 | (R)-(+)-Bay K 8644 | Calcium Channel , PPAR |
(R)-(+)-Bay-K-8644 is a Ca2+ channel agonist, a dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism o... | |||
T68086 | Imitrodast | Thrombin | |
Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiovascular diseases, and can be used in studies of arterial th... | |||
T0839 | Ketoprofen | RP-19583 | Apoptosis , COX , MRP |
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas... |